Clinical apheresis procedures. Our Clinical Therapeutic Apheresis team has experience in a wide range of apheresis procedures and can provide 24/7 support to medical facilities. It involves the separation and removal of The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA) Special Issue Writing Com-mittee is charged with reviewing, updating, and categorizing indications for the evidence-based use of therapeu-tic apheresis in human disease. , 2010. Since the 2007 JCA Special Issue (Fourth Edition), the Committee has incorporated systematic review and evidence-based approaches in the grading and The Division also provides 24-hour consultation, execution, and monitoring of therapeutic apheresis procedures to all UC Davis clinical services, as well as other health systems in the greater Sacramento area. Learn more about this procedure. Using technology called an apheresis machine, our nurses perform a comprehensive portfolio of procedures, to save and improve patients' lives. In hematologic practice, apheresis procedures are used to mitigate hyperviscosity in monoclonal protein disorders or remove pathologic ASFA is an organization of physicians, scientists, and allied health professionals whose mission is to advance apheresis medicine for patients, donors and practitioners through education, evidence-based practice, research and advocacy. section provides basic criteria for discontinuation of apheresis procedures (i. This handbook has three new chapters focusing on how to handle This volume has been significantly reorganized and updated to focus specifically on therapeutic apheresis. Subsequent chap-ters cover current instrumentation including devices used for therapeutic procedures out-side of the United States (Chapter 2), basic principles of therapeutic apheresis (Chapter 3 Apr 17, 2025 · The American Society for Apheresis (ASFA) has developed practical guidelines for therapeutic apheresis, acknowledging ongoing challenges in quality assessment and translating recommendations into clinical practice [8, 9]. Content addressing donor apheresis and cellular therapy are addressed in separate volumes. Clinical Apheresis FAQ What is apheresis (hemapheresis)? Jul 15, 2025 · Prior to the initiation of a course of apheresis procedures, clinical assessment and laboratory results must be suitably documented and a therapeutic apheresis treatment plan must be produced (1C). Feb 3, 2023 · Updated in February 2023, Chapter 14 of the Clinical guide to transfusion reviews information on indications, rationale, and techniques for therapeutic apheresis procedures, as well as the care of the apheresis patient. This targeted approach minimizes side effects and is also used Nov 28, 2024 · Apheresis is a medical procedure that involves removing whole blood from a patient or donor and separating it into individual components so that one particular component can be removed or modified. Nationwide, the American Red Cross performs more than 10,000 therapeutic apheresis procedures per year. This webpage discusses therapeutic apheresis, including plasma exchange and cytapheresis, with a focus on indications and technology. Jun 7, 2016 · Apheresis is a vital but little-known procedure that can be undertaken by nurses who have the necessary skills to understand the process and how to perform it successfully Abstract Therapeutic apheresis is a relatively unfamiliar area of nursing practice. The practical definition is a procedure in which blood is removed, a portion is UT Southwestern Medical Center offers therapeutic apheresis for patients with various conditions, including hematological, neurological, kidney, and skin disorders. The first half of the book covers the history of therapeutic apheresis, current instrumentation, basic principles, clinical consultation, and patient management. Therapeutic apheresis yields benefits in a variety of medical Dec 8, 2012 · Plasma exchange is a therapeutic procedure used to treat a variety of diseases through the bulk removal of plasma. Since the early 1970s, technological advances have produced apheresis machines that are substantially easier to operate. , 2005) and more procedures taking place out-side the UK Transfusion Services, such as allogeneic and autol-ogous haemopoietic progenitor cells–apheresis (HPC-A; also known as peripheral blood stem The document outlines the ASFA guidelines for therapeutic apheresis indications and categories, procedures like plasma exchange and photopheresis, and considerations for evaluating new patients and managing risks. It involves the separation and removal of Clinical apheresis is a medical procedure that selectively removes certain blood components to treat various conditions, such as autoimmune diseases and blood disorders. Apheresis center training programs | Spectra OptiaAbout Successions training Our advanced apheresis educational workshops are presented by a team of senior clinical specialists and technical excellence leaders with a deep understanding of apheresis therapeutic protocols and processes on the Spectra Optia system. Quality Assurance section provides basic criteria for discontinuation of apheresis procedures (i. Prior to the initiation of a course of apheresis procedures, clinical assessment and laboratory results must be suitably documented and a therapeutic apheresis treatment plan must be produced (1C). These procedures can alter the immune system, both humoral and cellular The last BCSH Guideline relating to apheresis was published approximately 17years ago (BCSH Joint Working Party of the Transfusion and Clinical Haematology Task Forces, 1998). Find answers to common questions about what apheresis entails and what to expect during apheresis procedures. Request and schedule both Cell Salvage (PAT) and Therapeutic Apheresis procedures at your hospital 24/7 with NYBCe's Clinical Force. In some instances, the number of procedures/series which may be reasonably employed in the particular clinical situation is suggested based upon currently available data. In hematologic practice, apheresis procedures are used to mitigate hyperviscosity in monoclonal protein disorders or remove pathologic Apheresis is a technology that separates donated blood components to treat certain illnesses. In the Ninth Edition, the JCA Special Issue Writing Committee has incorporated systematic review and evidence-based approaches in the grading of evidence and categorization of apheresis indications to make recommendations on the use of apheresis in a wide variety of diseases and con-ditions. Leukapheresis or lymphocytapheresis also describes apheresis procedures in which the white blood cells are isolated and retained. Volume 1 focuses specifically on therapeu-tic apheresis. Feb 26, 2025 · The American Society for Apheresis (ASFA) guidelines present a critical review of the medical literature, offering evidence-based recommendations for the use of apheresis procedures in clinical practice. ASFA is an organization of physicians, scientists, and allied health professionals whose mission is to advance apheresis medicine for patients, donors and practitioners through education, evidence-based practice, research and advocacy. For handling all social, emotional and ethical aspects during Apheresis - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version. Vitalant, a leader in therapeutic services, we provide apheresis procedures to treat a variety of diseases and special blood products in transfusion medicine. The replacement fluids/cells or modified components, along with the remainder of the blood, are then returned to the patient. The frequency of plasma exchange, the volume to be removed, the replacement fluid, and other variables are individualized. We offer leukocyte and platelet depletion, plasma exchange and RBC exchange. Therapeutic apheresis services are a consultative service provided to hospitals under a contractual agreement. With four spacious treatment pods, this newly renovated center is designed to enhance both the comfort of our donors and the efficiency of our stem cell collection process. From clinical apheresis to laboratory services, and more, Vitalant can help. The first chapter provides an overview of the history of therapeutic appli-cations and the development of evidence-based clinical guidelines. May 27, 2015 · The scope has been extended into a comprehensive description of best practise in Clinical Apheresis. ImpactLife is licensed by the US Food and Drug Administration and accredited by AABB. The types of apheresis procedures we perform include: Therapeutic plasma exchange, which removes and replaces plasma Photopheresis, which collects and treats white blood cells Red blood cell exchange, which removes and replaces red Jul 15, 2025 · Since the publication of the previous BSH apheresis guideline in 2015, 1 there have been a number of changes affecting workload and clinical practice for most apheresis services. The guidelines also outline the roles of healthcare professionals and the importance Summary Kalantari, Kambiz. To facilitate a prompt start to the procedure, the clinical team must coordinate efforts with several services, including those that perform the In 2019, the American Society for Apheresis (ASFA) released the eighth edition of its special issue on therapeutic apheresis in clinical practice. It involves the separation and removal of blood components and constituents for direct or indirect treatment of conditions spanning a wide range of clinical specialties; it requires a particular set of technical skills and specialised knowledge. Published jointly by AABB and the American Society for Apheresis (ASFA), Therapeutic Apheresis: A Handbook provides a thorough yet succinct account of the most commonly practiced apheresis procedures, indications for their use, and treatment recommendations for the diseases discussed. Trusts should identify a single individual as an apheresis lead, regardless of whether apheresis services are provided internally or by another organisation. Support is available 24 hours a day, seven days a week The American Red Cross is a trusted leader in clinical apheresis services, supporting hospitals through our responsiveness, national network, and commitment to patient satisfaction— empowering hospitals to provide exceptional patient care. That’s why we serve urgent and routine patient needs where you need us most – at the bedside. It involves drawing blood, separating it into its components, extracting harmful substances like excess cells or antibodies, and returning the rest to the patient. This article summarises the procedure, when it is used, and the specialist Jun 11, 2020 · NHS Blood and Transplant (NHSBT) Therapeutic Apheresis Services (TAS) provide treatment for both adults and children across a range of clinical specialties. 2 days ago · Explore Vivian’s Apheresis Nurse Career Guide to learn about salaries, job opportunities, available certifications, licensure requirements, desirable locations and more. Hoxworth’s Apheresis Center is located on the 4th floor of our Central location, 3130 Highland Avenue, Cincinnati, Ohio 45267, is a state-of-the-art facility that opened on July 7, 2022. The practice of clinical apheresis has become more widespread in the UK rather than remaining confined to a few highly focused units. Considering the complexity of the pathophysiologic characteristics of various clinical entities and in particular sepsis, apheresis methods are becoming increasingly applicable. ImpactLife's Patient Services team of physicians and specialty trained nurses provides safe, effective care throughout the procedure. Jul 15, 2025 · Since the publication of the previous BSH apheresis guideline in 2015, 1 there have been a number of changes affecting workload and clinical practice for most apheresis services. To apply this treatment to patients appropriately, it is essential to understand the methods to remove plasma, its effects on normal plasma constituents, the role of replacement fluids in the treatment, and the risks associated with the procedure. Chapter 1 reviews fundamental concepts of therapeutic apheresis, including the basics of the extracorporeal circuit, the physiology of apheresis, blood separation, vascular access, anticoagulation, clinical decision-making, the ASFA Choosing Wisely Campaign, and the complications associated with thera-peutic apheresis procedures. In most cases, the disorders so treated are characterized by a specific qualitative or quantitative abnormality of the blood. British Committee for Standards in Haematology The HATS Therapeutic Apheresis program supports a number of highly active clinical services and programs at Johns Hopkins Hospital, including Hematology/Oncology, Neurology, BMT Program, Solid Organ Transplantation and approved Clinical Studies. In conjunction with those Guidelines, this handbook rep-resents an essential tool for every apheresis physician, nurse, and related support personnel. Clinicians typically follow the Guidelines on the Use of Therapeutic Apheresis in Clinical Practice from the American Society for Apheresis (1). 8 Institute of Healthcare informatics, University College London Clinical Services, NHS Blood and Transplant, London, UK. Abstract Apheresis is a term for a group of extracorporeal treatments in which blood is separated into its components, with some components being discarded and replaced or subsequently modified. Here, our highly skilled apheresis SUMMARY Therapeutic apheresis refers to several blood processing methods that are used in the treatment of diverse clinical conditions. All procedures were carried out at bedside under the direct supervision of a trained apheresis technician and residents of the relevant clinical services. Careers in Apheresis Meet Deanna Duvall: Therapeutic Apheresis Nurse I am a Therapeutic Apheresis Nurse What is your nursing specialty? I am an apheresis nurse. It contains representative examples of apheresis practice SOPs from a variety of hospitals and/or blood centers. It often involves narrowed or blocked blood vessels, which can lead to chest pain, heart attacks, or strokes. It emphasizes evidence-based practices for therapeutic apheresis, including specific recommendations for plasma exchange in various medical conditions. Vitalant Therapeutic Services is a national leader in providing blood therapeutic services related to stem cell collection for treatment of a variety of blood cancers and other diseases. The survey was distributed to apheresis physicians and apheresis supervisors. Apheresis: Principles and Practice AABB: Standards for Cellular Therapy Services, 6th edition, 2013. "The choice of vascular access for therapeutic apheresis. Our program is staffed with skilled apheresis physicians and nurses committed to providing the highest quality patient care. These updated guidelines help practitioners choose when to initiate therapy and, equally important, when to reduce or stop apheresis practices where there is questionable benefit with no established evidence, or even harm. Apheresis is a procedure that enables healthcare providers to obtain or remove red blood cells, white blood cells, platelets and plasma for medical treatment. 3 (2012): 153-159. Operators usually learn to operate the apheresis machine, but more and more attention needs to be paid to the non-technical aspects of an apheresis procedure. The blood is returned to the patient’s body immediately after purification. Guideline on the clinical use of apheresis procedures for the treatment of patients and collection of cellular therapy products. Oct 1, 2025 · Therapeutic apheresis is an extracorporeal blood purification procedure. As for the 2015 Guideline, the remit of the current guideline covers all plasma exchange regardless of equipment used, all thera-peutic procedures undertaken on cell separators, and any autolo-gous or allogeneic donor apheresis for procurement of cellular therapy products (CTPs) such as haematopoietic progenitor cell apheresis (HPC-A), but May 27, 2015 · Before initiating a course of apheresis procedures, clinical assessment and laboratory results must be documented and a written treatment plan should be produced. A personalized survey link was emailed to one individual specializing in clinical apheresis services at each institution (n = 68) to prevent duplicative responses. Jul 15, 2025 · 6 Cell Apheresis & Gene Therapies, NHS Blood and Transplant, Bristol, UK. Nov 28, 2024 · Apheresis is a medical procedure that involves removing whole blood from a patient or donor and separating it into individual components so that one particular component can be removed or modified. About 900 hospitals in more than two dozen states count on Vitalant to be prepared for day-to-day and unimaginable blood product needs. It’s also known as pheresis or hemapheresis. The objective of this guideline is to provide healthcare professionals with clear guidance on the use of clinical apheresis. Selective apheresis procedures have been developed to target specific molecules, antibodies, or cellular elements in a variety of diseases. Apheresis is an extracorporeal medical technology in which the blood of a patient is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation. The advantage of the selective apheresis procedures over conventional therapeutic plasmapheresis is preservation of other essential plasma components such as al …. SUMMARY Therapeutic apheresis refers to several blood processing methods that are used in the treatment of diverse clinical conditions. The second half of the book covers We understand the significance of apheresis services in the treatment of diseases, and in the research of leading-edge therapies. To be included in the guidelines, a critical mass of Red Cross Therapeutic Apheresis Services are helping professionals save lives in your community every day. Its working principle is the selective or semi-selective removal of pathogenic components from the patient's blood or plasma and not the administration of therapeutic drugs. Procedures such as plasmapheresis in donors are of shorter procedure time, but others will take many hours. , end points/outcomes, both clinical and laboratory). Blood tests are usually performed prior to the procedure, with the therapy itself taking anywhere from 2-4 hours. As for the 2015 Guideline, the remit of the current guideline covers all plasma exchange regardless of equipment used, all thera-peutic procedures undertaken on cell separators, and any autolo-gous or allogeneic donor apheresis for procurement of cellular therapy products (CTPs) such as haematopoietic progenitor cell apheresis (HPC-A), but Sep 23, 2023 · Apheresis is a medical procedure that involves the separation and selective removal or collection of specific components of blood or blood products from a patient's circulation. Current versions of apheresis equipment are less Oct 14, 2024 · Therapeutic Apheresis: A Handbook, Seventh Edition Jointly published by AABB and the American Society for Apheresis, Therapeutic Apheresis: A Handbook offers a comprehensive yet succinct overview of widely practiced apheresis procedures, their clinical indications and treatment recommendations. ABSTRACT The general medicine and critical care services often care for patients that require therapeutic apheresis. In hematologic practice, apheresis procedures are used to mitigate hyperviscosity in monoclonal protein disorders or remove pathologic The apheresis nurses also complete the apheresis temperature log (APH-31) pre and post procedure, any deviations in temperature are report to the lead apheresis nurse. In this chapter, the clinical applications of common procedures, such as therapeutic plasma exchange (TPE), red cell exchange (RBC Ex), leukocytapheresis, low-density lipoprotein and (LDL) apheresis, and their common diseases applicable for each procedure are explained. Readers will find up-to-date guidance on donor evaluation, CD34+ cell mobilization strategies, options and selection of In this chapter, the clinical applications of common procedures, such as therapeutic plasma exchange (TPE), red cell exchange (RBC Ex), leukocytapheresis, low-density lipoprotein and (LDL) apheresis, and their common diseases applicable for each procedure are explained. Learn about apheresis including apheresis procedure and side effects. Furthermore, such an increase in number and location of procedures has no doubt References Journal and Clinical Apheresis: Special Issue 6th Edition Therapeutic Apheresis Guidelines 2013 McLeod BC, Szczepiorkowski ZM, Weinstein R, Winters JL, eds. Here, our highly skilled apheresis Vitalant offers services to hospitals and healthcare partner nationwide including blood products, apheresis, laboratory services, and transfusion medicine services. - Download as a PPT, PDF or view online for free May 11, 2015 · The last BCSH Guideline relating to apheresis was published approximately 17 years ago (BCSH Joint Working Party of the Transfusion and Clinical Haematology Task Forces, 1998). " Journal of clinical apheresis 27. The updated guidelines aim Apr 16, 2023 · Clinical use of apheresis procedures for the treatment of patients and collection of cellular therapy products This guideline is an update to the archived BCSH guideline on the clinical use of cell separators (BCSH Joint Working Party, 1998). In 2014, clinical apheresis is a distinct subspecialty overlap-ping Haematology, Transfusion Medicine and Renal Medicine (Weinstein, 2007), with more procedures being carried out (Stegmayr et al. To facilitate the appropriate Jun 1, 2019 · Thousands of apheresis procedures are performed on a daily basis. Vitalant hospital Apheresis is a technology that separates donated blood components to treat certain illnesses. Apr 28, 2025 · The Journal of Clinical Apheresis publishes articles dealing with the basic research and clinical applications of hemapheresis and transfusion medicine. Today’s cell separators are highly automated using sophisticated micro processors and optic sensors to detect and maintain the interface, to control the pumps, and to direct the flow of blood components through the circuits. Spectra Optia Apheresis System Essentials Guide, Terumo BCT, Inc. e. These guidelines are periodically reviewed with the addition of new indications, retirement of some former indications and the provision of updated recommendations for current Procedures Apheresis/infusion units perform several types of procedures, including: Plasmapheresis Cytapheresis Liposorption Outpatient infusion and transfusion Plasmapheresis Plasmapheresis is a procedure in which a large portion of a patient's plasma is removed and discarded and replaced with fresh donor plasma or a protein solution (human ASFA is an organization of physicians, scientists, and allied health professionals whose mission is to advance apheresis medicine for patients, donors and practitioners through education, evidence-based practice, research and advocacy. Sep 12, 2025 · Best Practices of Apheresis in Hematopoietic Cell Transplantation (2020) World-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices. In 2019, the American Society for Apheresis (ASFA) released the eighth edition of its special issue on therapeutic apheresis in clinical practice. Their goal is to help more blood centers, apheresis centers, and hospitals improve May 27, 2015 · The remit of the current guideline, covering all plasma exchange regardless of equipment used, all therapeutic procedures undertaken on cell separators, and any autologous or allogeneic donor apheresis for procurement of cellular therapy products such as HPC-A, reflects a more contemporary definition of ‘Clinical Apheresis’. Over time, these conditions can cause the heart to weaken or fail. In hematologic practice, apheresis procedures are used to mitigate hyperviscosity in monoclonal protein disorders or remove pathologic May 27, 2015 · Before initiating a course of apheresis procedures, clinical assessment and laboratory results must be documented and a written treatment plan should be produced. Learn more. Therapeutic apheresis procedures can be performed in both the hospital (inpatient) and outpatient setting, depending on the condition. 9 Department of Haematology, University College London NHS Foundation Trust, London, UK. Cell collections are not included (those will be included in the second edition of Cellular Ther-apy: A Handbook). Abstract Purpose of review: For over 30 years, the American Society for Apheresis (ASFA) has published practice guidelines on the use of therapeutic apheresis in the Journal of Clinical Apheresis (JCA) Special Issue. The updated guidelines aim SUMMARY Therapeutic apheresis refers to several blood processing methods that are used in the treatment of diverse clinical conditions. This document provides updated guidelines on the clinical use of apheresis procedures for treating patients and collecting cellular therapy products in the UK. Oct 1, 2025 · The Guidelines on the Use of Therapeutic Apheresis in Clinical Practice (Ninth special issue) were updated by the American Society for Apheresis (ASFA) in 2023. What is plasma apheresis, therapeutic apheresis and platelets apheresis. This tool may be used to assist in writing and revising SOPs by institutions that perform, or plan to perform, apheresis procedures. ASFA represents a broad range of professionals involved in: donor apheresis, apheresis in transplantation & therapeutic apheresis. The procedure is performed in the Apheresis Unit by connecting your veins to a cell separator (‘apheresis machine’) by temporary insertion of two cannula needles in your veins. Apheresis procedures are performed for various hematologic, neurological, renal, autoimmune, metabolic, and other indications. Therapeutic apheresis is a relatively unfamiliar area of nursing practice. Sep 29, 2023 · Apheresis Cardiovascular Disease – Cardiovascular disease refers to a group of disorders affecting the heart and blood vessels. Nov 20, 2023 · Therapeutic Apheresis (TA) includes a broad spectrum of extracorporeal treatments applied in various medical specialties, including Intensive Care Unit (ICU). This handbook covers only ther-apeutic apheresis procedures. That statement is followed by “What is apheresis? Is that like dialysis?” Apheresis is derived from a Greek word “to take away” or withdraw. 7 EBMT, Barcelona, Spain. g9dx lxi3hy5 fa iki1bxd kq dgd1c a4u7y0 knqxp 9rpcfkw mzik