The nucleotides in dna are joined by blank bonds. These fragments are later joined together by DNA ligase.

The nucleotides in dna are joined by blank bonds. , Construction of a housing development can be used as a powerful metaphor for protein synthesis. Each DNA molecule contains two DNA strands, which are twisted around one another to make a spiral-like shape called the double helix. … Sep 14, 2022 · Nucleotides are joined together by covalent bonds between the phosphate group of one nucleotide and the third carbon atom of the pentose sugar in the next nucleotide. ) a covalent bond between the phosphate group of one nucleotide and the sugar group of the next nucleotide Nucleotides are held together by phosphodiester bonds, while the bonds between nitrogen bases are hydrogen bonds that allow them to unzip during replication and transcription. However, RNA consists of a single strand with a sugar-phosphate backbone studded with bases, while DNA has two strands forming a double helix with hydrogen bonds Jul 20, 2017 · When nucleotides join together to form a DNA strand, the connection involves a specific type of covalent bonding, known as a phosphodiester bond. A molecule of DNA is a bunch of nucleotide monomers, joined one after another into a very long chain. Hydrogen bonds between deoxyribose and phosphate. The bond between the phosphate group of one nucleotide and the sugar group of the next nucleotide is a phosphodiester bond. Each nucleotide is composed of a nitrogenous base, a five-carbon sugar (deoxyribose), and a phosphate group. , The nucleotides are joined to each other by an enzyme called DNA ________. 3). Answer to the Question The nucleotides along one side of a DNA molecule are connected to each other by covalent bonds between phosphate groups and sugar molecules. The important components of each nucleotide are a nitrogenous base, deoxyribose (5-carbon sugar), and a phosphate group (see Figure 1). Nucleotides are linked together in DNA and RNA by phosphodiester bonds [RO– (PO 2–)–OR′] between phosphate, the 5′-hydroxyl group on one nucleoside, and the 3′-hydroxyl group on another nucleoside. These complementary pairings are between the nitrogenous bases, where adenine (A) pairs with thymine (T) forming two hydrogen bonds, and cytosine (C) pairs with guanine (G) forming three hydrogen bonds. hydrogen bonds between base pairs B. , thymine cytosine and more. a. DNA Polynucleotide Deoxyribonucleic acid (DNA) is the nucleic acid that stores genetic information. The DNA Double Helix Structure has two strands. In the 1950s, Francis Crick and James Watson worked together Now let’s consider the structure of the two types of nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Jun 24, 2025 · Building Blocks: Nucleotides and the Phosphodiester Bond Before delving into the complexities of DNA and RNA, it is crucial to understand the fundamental building blocks that constitute these essential molecules. , New _______ position themselves along the parent strands through ________ base pairing. DNA (d eoxyribo n ucleic a cid) is a nucleic acid biomolecule made up of subunits called nucleotides. Explanation Covalent bonds are strong chemical bonds that involve the sharing of electron pairs between atoms. This structure allows DNA to store and transmit genetic information with great accuracy and reliability. The nitrogenous base can be a purine, such as adenine (A) and guanine (G), or a pyrimidine, such as cytosine (C) and thymine (T). There are four types of nitrogenous bases found in DNA nucleotides: adenine, guanine, cytosine, or thymine. identify, in general terms, the enzymatic hydrolysis products of nucleosides. What Is a Nucleotide? A nucleotide is an organic molecule that serves Just as proteins are biopolymers made of amino acids, the nucleic acids are biopolymers made of nucleotides, joined together to form a long chain. In DNA, these bonds form the backbone of the molecule, linking the sugar of one nucleotide to the phosphate group of the Mar 12, 2025 · Nucleotides are joined together by covalent bonds between the sugar of one nucleotide and the phosphate of the next. Mar 14, 2024 · The two strands of a DNA molecule are held together by hydrogen bonds between the complementary base pairs of nucleotides from opposing strands. peptide bonds D. ionic phosphodiester hydrogen peptide glycosidic and more. May 18, 2025 · Because DNA polymerase can only add nucleotides in the 5’ to 3’ direction, replication is continuous on one strand (the leading strand) and discontinuous on the other (the lagging strand), which is synthesized in short segments called Okazaki fragments. Covalent bonds between deoxyribose and the nitrogen bases. hydrogen bonds between adenine and 2 days ago · A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder. Nucleotides can be further broken down to a phosphate group (PO 4-3) and a nucleoside which is composed of a aldopentose sugar (a sugar with five carbon atoms), and a heterocyclic purine or Study with Quizlet and memorize flashcards containing terms like The two strands of a DNA molecule are held together by ________ bonds between their base pairs. b. The DNA nucleotides are joined by phosphodiester bonds between the phosphate group of one nucleotide and the sugar molecule of the next. Scientists refer to nucleotides by the first letter of their base (A, G, C, and T, respectively). The building blocks of DNA are nucleotides, which are made up of three parts: a deoxyribose (5-carbon sugar), a phosphate group, and a nitrogenous base (Figure 9. Each nucleotide is composed of a nucleoside bonded to a phosphate group, and each nucleoside is composed of an aldopentose sugar linked through its anomeric carbon to the nitrogen atom of a heterocyclic purine or pyrimidine base. The nucleotides are joined together by covalent bonds between the phosphate of one nucleotide and DNA is a polymer made of monomeric units called nucleotides (Figure 1 A), a nucleotide comprises a 5-carbon sugar, deoxyribose, a nitrogenous base and one or more phosphate groups. Select one or more: a. These fragments are later joined together by DNA ligase. In this polynucleotide chain, the nucleotides are connected to each other by covalent bonds between phosphate group of one nucleotide and third carbon atom of** deoxyribose sugar** and forms a **phosphate backbone **of DNA. Jul 30, 2024 · The two strands of nucleotides in a DNA molecule are held together by: A. Chargaff Study with Quizlet and memorize flashcards containing terms like The bonds or interactions that hold together adjacent nucleotides in the sugar-phosphate backbone of DNA are _________, The bonds or interactions that hold together complementary bases from opposite strands of DNA are _________, The bonds or interactions between stacked nucleotide units that help hold the DNA molecule together Oct 4, 2019 · Nucleotide structure is simple, but the structure they can form together is complex. 1 Outline DNA nucleotide structure in terms of sugar (deoxyribose), base and phosphate. The nucleotides that comprise DNA contain a nitrogenous base, a deoxyribose sugar, and a phosphate group which covalently link with other nucleotides to form phosphodiester bonds. Apr 17, 2023 · Adjacent nucleotides in the same DNA strand are joined by a unique type of covalent bond called a phosphodiester bond, which forms between the phosphate group of one nucleotide and the sugar group of the next nucleotide. In addition, some stretches of nucleotides are involved in regulating when and how strongly those genes are Each nucleotide is joined to the next nucleotide in the chain by these strong bonds, forming a long chain of nucleotides that are very difficult to break apart. Two strands of a DNA molecule are held together by hydrogen bonds that form between the complementary nitrogen bases of the nucleotides. Nitrogenous base The nitrogenous base is the central information Study with Quizlet and memorize flashcards containing terms like A segment of DNA encoding a protein or an RNA molecule is a ________. There are four nitrogenous bases in DNA, two … The nucleotides are joined together in a chain by covalent bonds known as phosphodiester bonds. Each strand has a backbone made of alternating sugar (deoxyribose) and phosphate groups. Nov 28, 2023 · Polynucleotides are the fundamental building blocks that make up our genetic material. In a DNA or RNA strand, nucleotides are linked together by phosphodiester bonds. hydrogen bonds that link the complementary bases between the two DNA strands only. sugar and phosphate bonding C. To know more about** DNA :** DNA monomers are called nucleotides Just like a sentence “polymer” is composed of letter “monomers,” a DNA polymer is composed of monomers called nucleotides. 3. Deoxyribonucleic acid is a polymer chain of nucleotides connected by 5’ to 3’ phosphodiester bonds. One end of the nucleic acid polymer has a free hydroxyl at C3′ (the 3′ end), and the other end has a phosphate at C5′ (the 5′ end). This bond that connects one nucleotide to another is called the 3',5 DNA (d eoxyribo n ucleic a cid) is a nucleic acid biomolecule made up of subunits called nucleotides. The building blocks for DNA synthesis contain three phosphate groups, two are lost during this process, so the DNA strand contains one phosphate group per nucleotide. Kossel f. This creates a sugar-phosphate backbone of the DNA strand. The building blocks of DNA are nucleotides. Objectives After completing this section, you should be able to outline the relationship between nucleic acids, nucleotides and nucleosides. The nucleotides within each strand are joined together through covalent (specifically phosphodiester) bonds between the phosphate group of one nucleotide and the carbon atom in position 3 of the deoxyribose sugar of the next nucleotide. Plectonic, The nucleotides along each strand of DNA are joined by ____ bonds. C. phosphate A strand of DNA is a polymer of nucleotides, joined by covalent bonds between the deoxyribose of one monomer and the _______ of the next Jan 21, 2021 · The nucleotides that make up DNA are joined together like a long string of beads, called a DNA strand. This page outlines the structure of the nucleotide, how phosphodiester bonds form, the DNA helix, and how DNA and RNA differ from one another. This means that the data stored in DNA has to be stable, accurate, and easy to copy. Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. Phosphodiester c. This forms a nucleic acid strand with alternating sugar and phosphate molecules, which is referred to as the sugar-phosphate backbone. Each strand is made up of a polynucleotide chain consisting of a Deoxyribose Pentose Sugar attached to Phosphate group with Nitrogenous bases (Adenine, Guanine, Cytosine, Thymine) being projected from the strand. Jul 19, 2023 · There are several interactions present within a strand (intrastrand interactions) and between two strands (interstrand) that stabilize DNA. Figure \ (\PageIndex {1}\). The bonding causes the two strands to spiral around each other in a shape called a double helix. Study with Quizlet and memorize flashcards containing terms like During DNA replication, the two strands separate as the ____ bonds connecting the parent strands are broken by an enzyme called _____. Jan 30, 2025 · The structure of DNA is essential for its function. Jan 26, 2021 · The hydrogen bonds in DNA play a crucial role in the molecule's structure and function. explain the structural difference between the sugar components of DNA and RNA. See full list on rwu. D. 2 State the names of the four bases in DNA. The nucleotides of DNA consist of a deoxyribose sugar molecule to which is attached a phosphate group and one of four nitrogenous bases: two purines (adenine and guanine) and two pyrimidines (cytosine and thymine). Are adjacent nucleotides in the same DNA strand held together by covalent bonds? Study with Quizlet and memorize flashcards containing terms like Nucleotide, Complimentary Base Pairing, What bond holds together complementary bases from opposite strands of DNA are and more. This results in a repeating pattern of sugar-phosphate-sugar-phosphate, which is called the. carbon-to-carbon bonds in the sugar portion of the nucleotides. In their seminal 1953 paper, Watson and Crick unveiled two aspects of DNA structure: pairing the The DNA molecule is a polymer of nucleotides. I can show how this happens perfectly well by going back to a simpler diagram and not worrying about the structure of the bases. Hydrogen bonds between adenine and thymine and cytosine and guanine. DNA and RNA are the nucleic acids found in cells. The covalent bonds between the nucleotides create a strong and stable backbone for the molecule, and the hydrogen bonds between the base pairs hold the two strands of DNA together. Nucleotides are joined together to form nucleic acids through the phosphate group of one nucleotide connecting in an ester linkage to the OH group on the third carbon atom of the sugar unit of a second nucleotide. These bonds link the sugar and phosphate groups of adjacent nucleotides, creating a strong backbone for the nucleic acid strands. In addition to the strong covalent bonds that hold polynucleotide chains together, bases along a polynucleotide chain can form hydrogen bonds with bases on other chains (or with bases elsewhere on the same chain, as with secondary DNA (d eoxyribo n ucleic a cid) is a nucleic acid biomolecule made up of subunits called nucleotides. The bonds are called phosphodiester bonds. Watson b. Nucleotides are joined together through the phosphate group of one nucleotide linked to the OH group on the third carbon atom of the sugar of a second nucleotide. This molecule consists of two strands which wrap around each other, forming hydrogen bonds in the middle of the structure for support. Jun 9, 2023 · The sugar-phosphate backbone forms the structural framework of the DNA molecule. The C-G pair forms three. Nov 24, 2024 · True. May 6, 2025 · The nucleotides in a base pair are complementary which means their shape allows them to bond together with hydrogen bonds. RNA is the nucleic acid responsible for using the genetic information in DNA to produce proteins. The hydrogen bonding between complementary bases holds the two strands of DNA together. A DNA nucleotide has three components: a 5-carbon sugar (deoxyribose), a phosphate group, and a nitrogenous base. amino acid c. Below is an image of DNA. In RNA, the nucleotides are also joined by phosphodiester bonds. hydrogen b. Adenine, Guanine, Cytosine and Thymine. Type of bond that holds adjacent nucleotides together and is formed via a dehydration synthesis reaction. In addition, some stretches of nucleotides are involved in regulating when and how strongly those genes are Jan 10, 2025 · So nucleotides are joined by phosphodiester bonds between the three prime hydroxyl group of one nucleotide to the five prime phosphate group of the next nucleotide. Nov 10, 2021 · Another nucleotides are added in same manner to form polynucleotide chain. Select one: a. DNA monomers are called nucleotides Just like a sentence “polymer” is composed of letter “monomers,” a DNA polymer is composed of monomers called nucleotides. Together, the phosphate groups and sugars form the sugar-phosphate backbone, which makes up the outside of the DNA molecule. A covalent bond forms between the sugar of one nucleotide and the phosphate group of another nucleotide. phosphate d. Each nucleotide within has a specific structure which enables this formation. Find step-by-step Biology solutions and the answer to the textbook question The bonds that hold the two strands of DNA together come from a. Nucleotides are covalently bonded together to form the sugar-phosphate backbone. Just as proteins are biopolymers made of amino acids, the nucleic acids are biopolymers made of nucleotides, joined together to form a long chain. identify by name the four heterocyclic amine bases found in deoxyribonucleotides. Dec 21, 2020 · What do nucleotides bond together in DNA? Nucleotides form a pair in a molecule of DNA where two adjacent bases form hydrogen bonds. The bases are held together with hydrogen bonds. Study with Quizlet and memorize flashcards containing terms like 3. For this reason, the linkage in DNA or RNA strands is called a. no type of chemical bond. DNA normally exists as a two antiparallel complementary strands held together by hydrogen bonds between adenines (A) and thymines (T), and between guanines (G) and cytosines (C). The phosphate group links adjacent nucleotides in DNA and RNA through phosphodiester bonds. Take a look at what a nucleotide is, its structure, and its function in biological processes. In addition, some stretches of nucleotides are involved in regulating when and how strongly those genes are Study with Quizlet and memorize flashcards containing terms like During protein synthesis, tRNAs carrying amino acids bind to the ribosome at the _________blank. , What nitrogenous base in not found in RNA, Both DNA and RNA are usually double-standee molecules and more. the attraction of phosphate groups for each other b. ionic bonds that link the sugar and phosphate portions of the nucleotides in each Study with Quizlet and memorize flashcards containing terms like The sequence of bases in a nucleic acid is the primary structure. 3. covalent bonds between phosphate groups and sugar molecules. B. The 3' -OH of the sugar group forms a bond with one of the negatively charged oxygens of the phosphate group attached to the 5' carbon of another sugar. The nitrogenous bases that are bonded to the pentose sugars pair to each other by weak hydrogen bonds. Among enzymes required for DNA replication, ligases are needed to form _ _ _ _ _ _ bonds between nucleotides to join DNA segments. Study with Quizlet and memorize flashcards containing terms like The bonds or interactions that hold together adjacent nucleotides in the sugar-phosphate backbone of DNA are, The bonds or interactions that hold together complementary bases from opposite strands of DNA are, The bonds or interactions between stacked nucleotide units that help hold the DNA molecule together are and more. A nucleotide is formed when a sugar molecule is joined to a phosphate group and a nitrogen base. The phosphate group on one nucleotide links to the 3' carbon atom on the sugar of another one. The structure of the DNA helix is key to being able to understand how DNA functions and how it is replicated. Relate each metaphorical word or Study with Quizlet and memorize flashcards containing terms like The purines of both DNA and RNA include ___ and guanine, The pyrimidines of DNA include cytosine and, The ___ group of a DNA nucleotides is attached to the 5' carbon atom of the deoxyribose sugar molecule and more. The bonds or interactions that hold together adjacent nucleotides in the sugar-phosphate backbone of DNA are phosphodiester bonds. This bond forms between the phosphate group of one nucleotide and the 3' hydroxyl group of the sugar of another nucleotide. The specific sequence of nucleotides within these chains encodes the genetic information that The polynucleotides chains that make up DNA and RNA form via covalent bond * s between sugar and phosphate subunits of neighboring nucleotides along a chain. The phosphate group in nucleotides is a phosphorous atom bound to four oxygen atoms, providing a negative charge to the nucleotide molecule. In addition, some stretches of nucleotides are involved in regulating when and how strongly those genes are DNA nucleotides are joined together by blank bonds between the sugar and phosphate groups to make a single dna strand while the two strands of dna that make up the double helix are held to one another by blank bonds BUY Human Anatomy & Physiology (11th Edition) 11th Edition Feb 3, 2025 · Nucleotides are the basic building blocks of DNA and RNA, and they are held together by bonds between their phosphate, sugar, and nitrogenous base components. These covalent bonds form a continuous chain of nucleotides in a single strand of DNA. Joining the nucleotides into a DNA strand A DNA strand is simply a string of nucleotides joined together. Nucleic acids are composed of nucleotides, each of which contains a pentose sugar, a phosphate group, and a nitrogenous base. Uracil (U) is also a Nucleotides along each strand of DNA are joined by phosphodiester bonds, where the 5' phosphate group of one nucleotide is connected to the 3' hydroxyl group of another. The ability of DNA to function as the material through which genetic information is stored and transmitted is a direct result of its elegant structure. Sulfide, X-ray diffraction experiments conducted by ____ led to the determination of the structure of DNA. The repeating, or monomer, units that are linked together to form nucleic acids are known as nucleotides. Nucleotides are ubiquitous in biology, serving as the foundation of genetic material and fulfilling other essential roles in cells. DNA is made of two strands of nucleotides bonded together at their nitrogen-containing bases. Take a look at hydrogen bonds (and other molecular forces) as they relate to DNA molecular structure. Multiple Choiceionichydrogenweak chemicalcovalentpeptide Nov 27, 2023 · Nucleotides are nucleosides with one or more phosphate groups attached, forming nucleotide monophosphates, diphosphates, or triphosphates. Attached to each sugar is one of four bases: adenine (A Aug 31, 2023 · A nucleotide is an organic molecule made of a nitrogenous base, pentose sugar, and phosphate group. DNA Structure: DNA is composed of two long chains of nucleotides forming a double helix. Strands of DNA are made by joining sugar and phosphate as backbone (by phosphodiester bonds): two such DNA strands run antiparallely forming the sides of a ladder and the paired bases act as the rungs of the ladder. In addition, some stretches of nucleotides are involved in regulating when and how strongly those genes are Click the card to flip 👆 nucleotides joined into long strands or chains by covalent bonds Click the card to flip 👆 1 / 17 Jun 12, 2023 · The remarkable structure of deoxyribonucleic acid (DNA), from the nucleotide up to the chromosome, plays a crucial role in its biological function. Study with Quizlet and memorize flashcards containing terms like DNA is a nucleic acid made up of, DNA nucleotide is a unit made up of, What kind of bond keeps the nucleotides joined and more. Crick c. The deoxyribonucleic acid (DNA) of a typical mammalian cell contains about 3 × 10 9 nucleotides. DNA Structure - Learn how these tiny molecular forces known as hydrogen bonds stabilize the DNA double helix structure. Oct 18, 2025 · Each strand of a DNA molecule is composed of a long chain of monomer nucleotides. identify by name The nucleotides combine with each other by covalent bonds known as phosphodiester bonds or linkages. Nucleotides in a single DNA chain are joined together by a. pressbooks. These building blocks polymerize to form polynucleotides, creating the backbone of nucleic acids like DNA and RNA. This produces an alternating backbone of sugar – phosphate – sugar – phosphate all along the polynucleotide chain. The structure of DNA is called a double helix, which looks like a twisted staircase. These complex biomolecules consist of long chains of nucleotides joined together through phosphodiester bonds, creating the structural backbone of both DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). strong bonds between nitrogenous bases and deoxyribose c. This page will review the structure of the DNA helix and the many researchers who were … nucleotides A strand of DNA is a polymer of deoxyribose A strand of DNA is a polymer of nucleotides, joined by covalent bonds between the _______ of one monomer and the phosphate of the next monomer. The phosphate group attached to the 5' carbon atom of one nucleotide connects to the hydroxyl group (3'-OH) on the 3' carbon of the next nucleotide, forming the sugar-phosphate backbone of the nucleic acid. True or False, The backbone of a nucleic acid is the nitrogen bases. What three parts make a Nucleotides are joined together to form nucleic acids through the phosphate groups. pub Adenine always bonds with thymine, and cytosine always bonds with guanine. Each nucleotide is named depending on its nitrogenous base. Color the new strand (including the bases) BLUE What are the sides of the DNA ladder made of? 5 carbon sugar and phosphate parts of the nucleotide. The **covalent bonds between the sugar of one **nucleotide and the phosphate of the next nucleotide create a strong and stable linkage, known as a phosphodiester bond. protein, Along one side of a DNA molecule, the nucleotides are connected to each other by a. True OR False, The nucleotides in the backbone of DNA are held together by __________ bonds. Nitrogen d. . Because of the structure of the nucleotides, DNA forms a twisted ladder shape called a double helix. Franklin e. and more. The bonds or interactions that hold together complementary bases from opposite strands of DNA are** hydrogen bonds**. Nucleotides make up an organism’s genetic information—certain stretches of nucleotides in a DNA molecule are genes, which encode the proteins that affect an organism’s traits. Study with Quizlet and memorize flashcards containing terms like phosphodiester, hydrogen, sugar, phosphate, sugar, hydroxyl and more. Specifically Individual nucleotides are linked together to form long chains, or strands, of nucleic acids through a specific type of covalent bond called a phosphodiester bond. A phosphate group connects two sugar molecules via ester bonds. Covalent bonds between adenine and thymine Study with Quizlet and memorize flashcards containing terms like hydrogen; helicase, nucleotides; complemenatary, polymerase and more. The phosphate residue is attached to the hydroxyl group of the 5′ carbon of one sugar of one nucleotide and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, thereby forming a 5′-3′ phosphodiester bond. Hydrogen b. 3 Outline how DNA nucleotides are linked together by covalent bonds into a single strand. weak hydrogen bonds between the nitrogenous bases d. ” DNA is made of two linked strands that wind around each other to resemble a twisted ladder — a shape known as a double helix. , The amino acids carried by the tRNA are eventually joined to one another by _________blank bonds. There are four types of nitrogenous bases in DNA. E. Covalent bonds between deoxyribose and phosphate. The nitrogenous bases point DNA is a double-stranded molecule. , 3. How are the adjacent nucleotides in a single strand of DNA joined together? A. Pick all that apply. Below is a diagram showing how nucleotides are linked to one another to form a strand. In the iconic double-helix structure, the strands are oriented antiparallel to each other, with the bases facing inwards. These are covalent bonds formed between the phosphate group of one nucleotide and the sugar molecule of the adjacent nucleotide. In addition, some stretches of nucleotides are involved in regulating when and how strongly those genes are The deoxyribose sugar joined only to the nitrogenous base forms a Deoxyribonucleoside called deoxyadenosine, whereas the whole structure along with the phosphate group is a nucleotide, a constituent of DNA with the name deoxyadenosine monophosphate. Color the old strands (including the bases) RED. Wilkins d. Question: In DNA, nucleotides are joined to each other by covalent bonds that link the sugar and phosphate portions of the nucleotides in each strand only. DNA. The main nucleotides of DNA and RNA are adenine, guanine, thymine, cytosine, and uracil. The sugar component Nucleotides join together through phosphodiester linkages between the 5' and 3' carbon atoms to form nucleic acids. The nucleotides in DNA and RNA are joined by covalent bonds known as phosphodiester bonds. Scientists already knew that nucleotides contain the same three important components: a nitrogenous base, a deoxyribose (5-carbon sugar), and a phosphate group (Figure 12 1 2). This section elucidates the structure of nucleotides, the monomeric units of nucleic acids, and the nature of phosphodiester bonds, which link these nucleotides together to form Study with Quizlet and memorize flashcards containing terms like hydrogen bonds between nucleotide bases, The leading strand is built continuously, and the lagging strand is built in pieces. In DNA replication, each strand of the original DNA serves as a template for the synthesis of a complementary … Study with Quizlet and memorize flashcards containing terms like adenine, thymine, cytosine, guanine are?, Differences between DNA and RNA, Nucleotides have? and more. strong ionic bonds Fill in the blank. The sugar and phosphate make up the backbone of the nucleotides and are bonded together by phosphodiester bonds. Deoxyribonucleotides within DNA contain deoxyribose as the pentose sugar. The A-T pair forms two hydrogen bonds. odkmt xnmg uuct skb qsp8d nek7jo 0eyd t7pe mtso80 fhgwey